{"id":6091,"date":"2023-09-08T18:07:30","date_gmt":"2023-09-08T18:07:30","guid":{"rendered":"https:\/\/cdafound.org\/?page_id=6091"},"modified":"2023-09-08T18:08:56","modified_gmt":"2023-09-08T18:08:56","slug":"the-new-paradigm-of-hepatitis-c-therapy-integration-of-oral-therapies-into-best-practices","status":"publish","type":"page","link":"https:\/\/cdaf.org\/zh\/publications\/the-new-paradigm-of-hepatitis-c-therapy-integration-of-oral-therapies-into-best-practices\/","title":{"rendered":"\u4e19\u578b\u809d\u708e\u6cbb\u7597\u7684\u65b0\u8303\u5f0f\uff1a\u5c06\u53e3\u670d\u7597\u6cd5\u878d\u5165\u6700\u4f73\u5b9e\u8df5"},"content":{"rendered":"<figure class=\"wp-block-image alignleft size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"101\" height=\"131\" src=\"https:\/\/cdafound.org\/wp-content\/uploads\/2023\/09\/image-4.png\" alt=\"\" class=\"wp-image-6092\" srcset=\"https:\/\/cdaf.org\/wp-content\/uploads\/2023\/09\/image-4.png 101w, https:\/\/cdaf.org\/wp-content\/uploads\/2023\/09\/image-4-9x12.png 9w\" sizes=\"auto, (max-width: 101px) 100vw, 101px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jvh.12173\/abstract\">Afdhal NH, Zeuzem S, Schooley RT \u7b49\u3002\u4e19\u578b\u809d\u708e\u6cbb\u7597\u7684\u65b0\u8303\u5f0f\uff1a\u5c06\u53e3\u670d\u7597\u6cd5\u878d\u5165\u6700\u4f73\u5b9e\u8df5\u3002\u300a\u75c5\u6bd2\u809d\u75c5\u6742\u5fd7\u300b2013\uff1b20\uff1a745-60\u3002<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u65b0\u5174\u6570\u636e\u8868\u660e\uff0c\u5168\u53e3\u670d\u6297\u75c5\u6bd2\u7597\u6cd5\u5728\u4e0d\u4e45\u7684\u5c06\u6765\u6709\u671b\u5e94\u7528\u4e8e\u6162\u6027\u4e19\u578b\u809d\u708e\u75c5\u6bd2 (HCV) \u6cbb\u7597\u3002\u5168\u53e3\u670d\u7597\u6cd5\u6709\u671b\u53d6\u4ee3\u5e72\u6270\u7d20\u7597\u6cd5\uff0c\u8010\u53d7\u6027\u66f4\u4f73\u3001\u7597\u6548\u66f4\u4f73\u3001\u7597\u7a0b\u66f4\u77ed\u4e14\u66f4\u6613\u4e8e\u7ed9\u836f\u3002\u4e0e\u65b0\u6cbb\u7597\u65b9\u6848\u540c\u6b65\u51fa\u73b0\u7684\u662f\u75be\u75c5\u7b5b\u67e5\u548c\u5206\u671f\u7684\u65b0\u65b9\u6cd5\uff0c\u8fd9\u4f7f\u5f97\u66f4\u53ca\u65f6\u7684\u62a4\u7406\u548c\u6cbb\u7597\u6210\u4e3a\u53ef\u80fd\u3002\u7ec4\u7ec7\u5b66\u635f\u4f24\u8bc4\u4f30\u901a\u5e38\u91c7\u7528\u809d\u6d3b\u68c0\uff0c\u4f46\u975e\u4fb5\u5165\u6027\u7ec4\u7ec7\u5b66\u635f\u4f24\u8bc4\u4f30\u5728\u4e00\u4e9b\u6b27\u6d32\u56fd\u5bb6\u5df2\u6210\u4e3a\u5e38\u6001\uff0c\u5728\u7f8e\u56fd\u4e5f\u6b63\u65e5\u76ca\u666e\u53ca\u3002\u6b64\u5916\uff0c\u7f8e\u56fd\u75be\u75c5\u63a7\u5236\u4e0e\u9884\u9632\u4e2d\u5fc3 (CDC) \u4e5f\u51fa\u53f0\u4e86\u65b0\u7684\u4e3e\u63aa\uff0c\u65e8\u5728\u7b80\u5316\u68c0\u6d4b\u6d41\u7a0b\uff0c\u63d0\u9ad8\u533b\u62a4\u4eba\u5458\u548c\u60a3\u8005\u7684\u610f\u8bc6\uff0c\u5e76\u5c06 HCV \u7b5b\u67e5\u5efa\u8bae\u6269\u5c55\u5230\u57fa\u4e8e\u98ce\u9669\u7684\u7b56\u7565\u4e4b\u5916\u3002CDC \u4e8e 2012 \u5e74\u53d1\u5e03\u7684\u5efa\u8bae\u65e8\u5728\u589e\u52a0\u7f8e\u56fd HCV \u8d1f\u62c5\u6700\u91cd\u4eba\u7fa4\u7684 HCV \u68c0\u6d4b\uff0c\u5efa\u8bae\u6240\u6709\u51fa\u751f\u4e8e 1945 \u5e74\u81f3 1965 \u5e74\u7684\u4eba\u8fdb\u884c\u4e00\u6b21\u6027\u68c0\u6d4b\u3002 2013\u5e74\uff0c\u7f8e\u56fd\u9884\u9632\u670d\u52a1\u5de5\u4f5c\u7ec4\u91c7\u7eb3\u4e86\u7c7b\u4f3c\u7684\u5efa\u8bae\uff0c\u9488\u5bf9\u57fa\u4e8e\u98ce\u9669\u548c\u51fa\u751f\u961f\u5217\u7684\u68c0\u6d4b\u3002\u7efc\u4e0a\u6240\u8ff0\uff0c\u7b5b\u67e5\u3001\u8bca\u65ad\u548c\u6cbb\u7597\u9886\u57df\u7684\u8fdb\u5c55\u53ef\u80fd\u4f1a\u589e\u52a0\u5bf9\u6cbb\u7597\u7684\u9700\u6c42\uff0c\u5e76\u523a\u6fc0\u6162\u6027\u4e19\u578b\u809d\u708e\u76f8\u5173\u62a4\u7406\u670d\u52a1\u7684\u8f6c\u53d8\uff0c\u4ece\u800c\u589e\u52a0\u521d\u7ea7\u4fdd\u5065\u548c\u4f20\u67d3\u75c5\u4e13\u5bb6\u7684\u53c2\u4e0e\u5ea6\u3002\u7136\u800c\uff0c\u5373\u4f7f\u5728\u8fd9\u4e2a\u65b0\u7684\u6cbb\u7597\u65f6\u4ee3\uff0c\u6cbb\u6108\u4e19\u578b\u809d\u708e\u60a3\u8005\u7684\u969c\u788d\u4ecd\u7136\u5b58\u5728\u3002\u514b\u670d\u8fd9\u4e9b\u969c\u788d\u9700\u8981\u521b\u65b0\u7684\u7efc\u5408\u6218\u7565\uff0c\u5e76\u5728\u5730\u65b9\u3001\u533a\u57df\u548c\u56fd\u5bb6\u5c42\u9762\u6295\u5165\u8d44\u6e90\u3002<\/p>","protected":false},"excerpt":{"rendered":"<p>Afdhal NH, Zeuzem S, Schooley RT, et al. The new paradigm of hepatitis C therapy: integration of oral therapies into best practices. J Viral Hepat 2013; 20: 745-60. Emerging data indicate that all-oral antiviral treatments for chronic hepatitis C virus (HCV) will become a reality in the near future. In replacing interferon-based therapies, all-oral regimens [&hellip;]<\/p>\n","protected":false},"author":939,"featured_media":0,"parent":2705,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"subtheme":[],"class_list":["post-6091","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/cdaf.org\/zh\/wp-json\/wp\/v2\/pages\/6091","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cdaf.org\/zh\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/cdaf.org\/zh\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/cdaf.org\/zh\/wp-json\/wp\/v2\/users\/939"}],"replies":[{"embeddable":true,"href":"https:\/\/cdaf.org\/zh\/wp-json\/wp\/v2\/comments?post=6091"}],"version-history":[{"count":1,"href":"https:\/\/cdaf.org\/zh\/wp-json\/wp\/v2\/pages\/6091\/revisions"}],"predecessor-version":[{"id":6093,"href":"https:\/\/cdaf.org\/zh\/wp-json\/wp\/v2\/pages\/6091\/revisions\/6093"}],"up":[{"embeddable":true,"href":"https:\/\/cdaf.org\/zh\/wp-json\/wp\/v2\/pages\/2705"}],"wp:attachment":[{"href":"https:\/\/cdaf.org\/zh\/wp-json\/wp\/v2\/media?parent=6091"}],"wp:term":[{"taxonomy":"subtheme","embeddable":true,"href":"https:\/\/cdaf.org\/zh\/wp-json\/wp\/v2\/subtheme?post=6091"}],"curies":[{"name":"\u53ef\u6e7f\u6027\u7c89\u5242","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}